FRIDAY: No. 3 Cheyenne East at No. 5 Cheyenne Central, 5 p.m.
WHERE: Riske Field.
LAST WEEK: The Thunderbirds (2-1) lost to Gillette 48-35; the Indians (1-2) lost to Natrona County 40-13.
LAST TIME: East defeated Central 21-14 on Sept. 16, 2011 at East. Central leads the all-time series 42-18 (since 1960).
KEY MATCHUP: Turnovers. The Indians turned the ball over seven times last week in a loss to Natrona County, and the Thunderbirds had three key giveaways in a loss to Gillette. Turnovers are always bigger in a rivalry game.
FRIDAY: Evanston at No. 4 Sheridan, 6 p.m.
WHERE: Homer Scott Field.
LAST WEEK: The Red Devils (1-2) defeated Rock Springs 21-14; the Broncs (2-1) defeated Cheyenne South 45-0.
LAST TIME: Sheridan defeated Evanston 42-35 on Sept. 16, 2011 at Evanston. Sheridan leads the all-time series 10-2 (since 1991).
KEY MATCHUP: The line of scrimmage. Both teams have had more success when able to control the trenches. The team can establish an edge on the lines may take control from the start.
FRIDAY: No. 2 Douglas at No. 3 Star Valley, 7 p.m.
WHERE: Braves Field.
LAST WEEK: The Bearcats (2-0) defeated Cody 15-10; the Braves (2-0) defeated Lander 68-0.
LAST TIME: Douglas defeated Star Valley 27-7 on Sept. 16, 2011 at Douglas. Douglas leads the all-time series 5-1 (since 1975).
KEY MATCHUP: Turnovers. Neither offense gives it away (one combined) and both defenses have done a good job forcing them (12 combined). A late turnover could swing the tide.
FRIDAY: No. 5 Green River at No. 4 Buffalo, 6 p.m.
WHERE: Bison Bowl.
LAST WEEK: The Wolves (1-1) defeated Riverton 34-28; the Bison lost to Powell 41-14.
LAST TIME: Buffalo defeated Green River 17-14 in overtime on Sept. 16, 2011 at Green River. The all-time series in tied 1-1 (since 1976).
KEY MATCHUP: Defense. The Bison play stout defense (No. 1 in 3A), even after last week's loss, but the Wolves have struggled (No. 9). A shootout fits Green River, but not if Buffalo shuts the door early.
FRIDAY: Wheatland at No. 4 Glenrock, 6 p.m.
WHERE: Sheldon Henderson Stadium.
LAST WEEK: The Bulldogs (2-0) defeated Wright 41-10; the Herders (2-0) defeated Tongue River 39-10.
LAST TIME: Glenrock defeated Wheatland 35-6 on Sept. 16, 2011 at Wheatland. The all-time series is tied 12-12 (since 1974).
KEY MATCHUP: Air vs. Ground. This game features Class 2A's top running offense (Glenrock) versus the top passing offense (Wheatland). The team can assert it's style of play could gain the upper hand from the start.
FRIDAY: No. 1 Lovell at No. 2 Lyman, 4 p.m.
WHERE: Eagle Stadium.
LAST WEEK: The Bulldogs (2-0) defeated Pinedale 55-31; the Eagles (2-0) defeated Kemmerer 46-6.
LAST TIME: Lovell defeated Lyman 21-13 in the Class 2A state championship on Nov. 11, 2011 at Laramie. Lovell leads the all-time series 6-4 (since 1994).
KEY MATCHUP: Fast start. The final score of the Bulldogs' first two games have been deceiving, thanks to big halftime leads. Therefore, the Eagles need to get out to a quick start and make Lovell play from behind.
FRIDAY: No. 3 Southeast at No. 2 Lusk, 7:30 p.m.
WHERE: Fullmer Stadium.
LAST WEEK: The Cyclones (1-0) were idle; the Tigers (2-0) defeated Hill City, S.D., 55-0.
LAST TIME: Southeast defeated Lusk 18-12 on Sept. 16, 2011 at Yoder. Lusk leads the all-time series 21-14 (since 1979).
KEY MATCHUP: Rust. The Cyclones were idle last week, following a Week One loss to Class 2A Newcastle, while Lusk absolutely drubbed Hill City (S.D.). Will a bye week help Southeast in the conference opener for both teams?
FRIDAY: No. 5 Shoshoni at Burlington, 3 p.m.
WHERE: Husky Stadium.
LAST WEEK: The Wranglers (2-0) defeated Wind River 13-9; the Huskies (1-1) defeated Saratoga 29-8.
LAST TIME: Shoshoni defeated Burlington 41-36 on Sept. 16, 2011 at Shoshoni. Shoshoni leads the all-time series 15-14 (since 1942).
KEY MATCHUP: Passing offense vs. Passing defense. The Wranglers are tops in Class 1A (181 yards per game) at throwing the ball. The Huskies (19 total yards allowed) are tops at defending the pass. Something will give.
SATURDAY: No. 3 Kaycee at Hulett, 2 p.m.
WHERE: Red Devil Stadium.
LAST WEEK: The Buckaroos (2-0) defeated Farson 65-6; the Red Devils (1-1) defeated Hanna 43-19.
LAST TIME: Kaycee defeated Hulett 38-27 on Sept. 17, 2011 at Kaycee. Kaycee leads the all-time series 1-0 (since 2011).
KEY MATCHUP: Defensive pressure. Both the Bucs and the Red Devils have had success getting into the opposition's backfield. Hulett (11 tackles for loss) and Kaycee (9) are 1-2 in six-man in that category.
SATURDAY: No. 2 Snake River at No. 5 Guernsey, 3 p.m.
WHERE: Viking Stadium.
LAST WEEK: The Rattlers (1-1) lost to Dubois 43-36; the Vikings (2-0) defeated Ten Sleep 38-32.
LAST TIME: Snake River received a forfeit victory against Guernsey on Sept. 17, 2011. Snake River leads the all-time series 2-0 (since 2010).
KEY MATCHUP: Momentum. The Vikings have it, after a last minute touchdown pushed them to a second straight victory. The Rattlers need to recapture it, after having their 22-game winning streak snapped last week in a loss to Dubois.